Several years ago, Kevin Esvelt pioneered the concept of using Crispr and gene drive technology to alter whole species. Today, he is researching ways to limit the spread of introduced gene drives and advocating for transparent and responsive science. In this interview, he discusses how and why to make science more open, and much else. Esvelt is an assistant professor in the MIT Media Lab, where he runs the Sculpting Evolution Group. Read this interview in the March/April issue of the digital Journal.