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Mark Leyse is a nuclear power safety advocate, focusing on fuel-cladding issues, severe accidents, and improving evaluations of postulated accidents. Safety issues he raised in a petition for rulemaking, PRM-50-84, contributed to a US Nuclear Regulatory Commission rulemaking on fuel-cladding behavior under reactor loss-of-coolant accident conditions—revisions to Section 50.46(b)—that was approved in 2012. In 2014, he wrote a report for Natural Resources Defense Council on unresolved problems associated with severe accident hydrogen generation.